3)Let’s explore BPG binding by hemoglobin a bit further! Download the PDB file for hemoglobin bound to BPG (PDB: 1B86) and open it up in PyMOL. Hint:…

3)Let’s explore BPG binding by hemoglobin a bit further! Download the PDB file for hemoglobin

bound to BPG (PDB: 1B86) and open it up in PyMOL. Hint: You can color the individual subunits

differently in order to most easily visualize the quaternary structure of hemoglobin. One way to do

this is to click on the selection line for the PDB (1B86), then click on menu button C (for color) and

select ‘by chain’.

a)Explain why we call BPG a “heterotropic allosteric modulator” of hemoglobin.

Leave a Reply