I have two questions: Prokaryotic cell is a single compartment, while eukaryotes have numerous organelles (compartment). They are all membrane bound…

I have two questions:

Prokaryotic cell is a single compartment, while eukaryotes have numerous organelles (compartment). They are all membrane bound organelles.  What is the origin of all these membrane bound organelles?

AND

What is unique about how pyruvate dehydrogenase is controlled and not true of α-ketoglutarate dehydrogenase?

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